Powdery mildew, caused by  Uncinula necator L. fungus, is one of the most important plant diseases that affect the grape crop and leads to a huge loss in the crop. Therefore, the main goal of the research was to design an integrated control program to combat the disease in addition to combating the rest of the plant diseases that appear on grapes, such as downy mildew, gray mold, and flower blight. The program was designed over 3 seasons (2022- 2024). In the first seasons,(2022), three chemical  fungicides control  programs (Proposed chemical control program, Mango modified chemical control program and Original chemical control program compared with general control which was untreated, all  chemical control programs were depended on different chemical groups were evaluated, including preventive, curative, and systemic. The most effective and efficient chemical  fungicides program  in decreasing the disease, was  proposed chemical, control program, which gave high efficiency in combating the powdery mildew ( 15, 18 and 21%)  Powdery mildew disease severity% , and associated diseases as the percentage of disease incidence  at the end of the season reached( 11,16% and 19%) fruit rot disease incidence %, ( in Flame, Superior  and Thompson ,respectively ,followed by Mango Modified chemical control  which decreasing  either Powdery mildew disease severity (21, 28 and 33%) or associated diseases incidence % (13 , 18 and 20%) in Flame ,Superior  and Thompson ,respectively,  comparison with general control which gave (33,39 and 30%)  , Also ,the proposed fungicides chemical control was reduced isolation frequency % of causal fruit rots Pathogens ,under specific farm condition ,comparison with control treatment. In the second and third seasons (2023 and 2024). Also, three  integrated control program were been tested  to companied  between  agricultural fertilizers and fungicide alternatives and in comparison with the control treatment. It was proven that the best results were obtained in the  Proposed integrated control program, which covered 0% disease severity of powdery mildew, in addition to the fact that the percentage of other diseases at the end of the training 0.0 % followed by Mango  modified integrated control program which covered ( 2.2 and 4%)  disease severity  of powdery  mildew  , in addition ,  1% Fruit rot disease incidence  compared to the control, which were (74 , 74 and 80 %) powdery mildew disease severity % and also   35%  Botrytis fruit rot disease induce % in  ( Film , Superior and Thomason ) grapes respectively.
Conclusively, the main objective of the research is to design an integrated control program to combat the powdery mildew of grape disease in addition to combating other associated diseases that appear on grapes, such as downy mildew, gray rot, and flower blight. Three integrated control programs were tested in the dormant stage to compare agricultural fertilizers and fungicide alternatives and compared with the control treatment. It was proven that the best results were obtained in the proposed integrated control program, which covered 0% of the severity of powdery mildew disease, in addition to the percentage of other diseases at the end of the experiment being 0.0%.