Abstract: Background: The rapid evolution of technology has profoundly influenced healthcare delivery and education, particularly in nursing. Virtual nursing, which includes telehealth, remote patient monitoring, and digital health education, has become a vital component of modern healthcare systems. Purpose To assess the knowledge and perceptions of virtual nursing among undergraduate nursing students at Benha University. Methods: A cross-sectional descriptive research design was employed. The study was conducted at the Faculty of Nursing, Benha University. Sampling A number of 380 nursing students were involved in the second (89), third (145), and fourth (146) academic years. Instruments: Two instruments were used for data collection (sociodemographic data, knowledge, and perception of virtual nursing). Results:  84.2% had a PC and 94.7% had internet access. Analysis of virtual nursing requirements showed strong recognition of essential technological tools, with internet connectivity being the most crucial requirement (92.9% agreement). Student perceptions were generally positive, 65% recognized the future importance of virtual nursing in healthcare and 75% believed it would facilitate communication. However, 40% expressed concerns about losing direct patient connection. Conclusion: The study highlights a significant relationship between technological access, academic progression, and understanding of virtual nursing concepts. The findings emphasize the importance of addressing the urban-rural digital divide and integrating virtual nursing education into the curriculum. The results provide valuable insights for developing targeted educational interventions and resource allocation strategies. Recommendations: Virtual nursing concepts should be integrated into nursing partnerships should be developed with technology departments.