The present study investigated the dietary effect of different turmeric powder (TUR) levels on growth performance, blood parameters, immune response, antioxidant status, gut morphology, and microbiological traits in broiler chickens during winter (December 2023 to January 2024). 160 broiler chicks, divided into 16 duplicates at random, were fed four experimental meals (0.0, 2, 4, and 6 g/kg) of turmeric powder, with 10 chicks per replicate and 4 replicates per treatment. Growth performance, slaughter test, and blood parameters were measured. The results showed that LBW and TBWG of 6-week-old chicks fed diets containing higher levels of turmeric powder (4.0 or 6.0 g/kg) increased significantly compared with the control group. At the same time, there were no significant effects on the FI or FCR of broiler chicks during the whole experimental period. On the other hand, significantly lower serum levels of LDL and MDA were recorded for broiler chickens supplemented with different levels of TUR compared with the control group. However, significantly the highest serum levels of TP and HDL were registered for birds supplemented with TUR at 6 g/kg compared with the control group. The jejunum of birds fed TUR-enriched diets (4.0 and 6.0 g/kg) showed a significant increase in villus height compared with the other groups. In contrast to the control group, there was a numerical rise in the total number of live bacteria. The performance and overall health of broiler chickens were found to be improved by TUR-containing dietary additives.