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386402

SPANLASTICS: A Unique Formulation Strategy in The Delivery of Pharmaceuticals-Carbapenems as a Model.

Article

Last updated: 08 Feb 2025

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Subjects

-

Tags

Pharmaceutics

Abstract

Drug delivery systems based on nanotechnology have been significant in surpassing the challenges associated with traditional dose forms. A promising drug delivery vehicle is spanlastics, an elastic nanovesicle that can transport a variety of drug compounds. Spanlastics have shown an increasing amount of interest in various forms of administrative pathways. They may squeeze themselves through skin pores because they are elastic and malleable, making them ideal for transdermal delivery. Non-ionic surfactants or mixtures of surfactants make up spanlastics. Numerous studies have demonstrated how spanlastics greatly improve drug toxicity, drug bioavailability, and therapeutic efficacy. Our future goal is to evaluate the spanlastic-encapsulated carbapenem's antibacterial and anti-biofilm characteristics. Following the isolation of Staphylococcus epidermidis isolates and the assessment of their microbiological sensitivity, the plate microtiter test was employed to investigate their capacity to form biofilms.

DOI

10.21608/jabps.2024.298914.1221

Keywords

Nanoparticles, spanlastics, spans, Edge Activators, carbapenems

Authors

First Name

Shadwa

Last Name

Ahmed Mousa

MiddleName

-

Affiliation

Department of Pharmaceutics, Faculty of Pharmacy, Minia University, 61519 Minia, Egypt. Department of Pharmaceutics, Faculty of Pharmacy, Merit University Egypt (MUE), Sohag, Egypt.

Email

shadwaabdelfattah@gmail.com

City

Minia

Orcid

-

First Name

Milad

Last Name

Qelliny

MiddleName

Reda

Affiliation

Pharmaceutics Department, Faculty of Pharmacy, Minia University, 61519 Minia, Egypt.

Email

mila_reda@mu.edu.eg

City

Minia

Orcid

0000-0001-7529-9578

First Name

Reham

Last Name

Ibrahem

MiddleName

Ali

Affiliation

Department of Pharmaceutics, Faculty of Pharmacy, Minia University, 61519 Minia, Egypt.

Email

reham.ali@mu.edu.eg

City

Minia

Orcid

-

First Name

Safy

Last Name

Hadiya

MiddleName

-

Affiliation

Assuit International Center of Nanomedicine, Al-Rajhy Liver Hospital, Assuit University, Assuit, 71515, Egypt.

Email

ph.s.h1989@gmail.com

City

Assuit

Orcid

-

First Name

Hatem

Last Name

Sarhan

MiddleName

A.

Affiliation

Department of Pharmaceutics, Faculty of Pharmacy, Minia University, 61519 Minia, Egypt.

Email

hatem.sarhan@mu.edu.eg

City

Minia

Orcid

-

First Name

Fatma

Last Name

Mady

MiddleName

Mohammed

Affiliation

Pharmaceutics Department, Faculty Of Pharmacy, Minia University, 61519 Minia, Egypt.

Email

fatmamady@hotmail.com

City

Minia

Orcid

0000-0002-2865-145x

Volume

7

Article Issue

4

Related Issue

53631

Issue Date

2024-10-01

Receive Date

2024-06-23

Publish Date

2024-10-01

Page Start

117

Page End

125

Print ISSN

2535-1869

Online ISSN

2535-2040

Article File

JABPS_Volume 7_Issue 4_Pages 117-125.pdf

PDF . 519.7kB

Link

https://jabps.journals.ekb.eg/article_386402.html

Detail API

http://journals.ekb.eg?_action=service&article_code=386402

Order

1

Type

Review Articles

Type Code

523

Publication Type

Journal

Publication Title

Journal of advanced Biomedical and Pharmaceutical Sciences

Publication Link

https://jabps.journals.ekb.eg/

MainTitle

SPANLASTICS: A Unique Formulation Strategy in The Delivery of Pharmaceuticals-Carbapenems as a Model.

Details

Type

Article

Created At

08 Feb 2025