Background: Low-Level Laser Therapy (LLLT) has emerged as a potential adjunctive treatment for bone fracture healing. This review aims to comprehensively examine the current state of knowledge regarding LLLT's effects on bone fracture healing.
Methods: This review explores the methodology of LLLT, including types of lasers, key parameters, and application methods. It also discusses the mechanisms of action at cellular, molecular, and tissue levels. A thorough analysis of clinical studies, including animal studies, human trials, and meta-analyses, is presented. Factors influencing LLLT efficacy and potential advantages and limitations are also examined.
Results: Many studies report positive effects of LLLT on bone fracture healing, including accelerated healing times, improved bone quality, and reduced pain. However, results are not universally consistent, likely due to variations in study designs, laser parameters, and outcome measures. The review highlights the need for standardization of protocols and larger-scale clinical trials.
Conclusion: While LLLT shows promise as an adjunctive therapy for bone fracture healing, more research is needed to fully establish its efficacy and optimal application. Future directions include standardization of protocols, large-scale clinical trials, optimization of treatment parameters, and exploration of combination therapies. As understanding of underlying mechanisms improves and technology advances, LLLT has the potential to become an increasingly valuable tool in fracture management.