Background: Obesity is a key risk factor for developing long-term health complications and global mortality. Lifestyle modifications including dietary intervention and increased physical activity can effectively treat obesity. This study aimed to evaluate the effect of mobile health teaching program about diet and exercise on obesity control among faculty of nursing students using Randomized Controlled Trial (RCT) design on intervention and control purposive computer-generated random sample of male and female students studying at different levels in the academic year (2023-2024) at the Faculty of Nursing, Miser for Science and Technology University; Egypt. The study employed three tools, Tool (I): Demographic information questionnaire, Tool (II): Self-administrated Structured KAP Questionnaire & Tool (III): Anthropometric Measurements Scale. The study results showed statistically significant improvement in the mean level of knowledge, attitude, and practices of the intervention group of students after 4 and 6 months of the mobile health teaching program implementation compared to the control group.  The study concluded that the mobile health teaching program about diet and exercise have positive effect on the faculty of nursing students' anthropometric measurements indicating obesity control. So, the study recommended investigating the effect of artificial intelligence social media applications on controlling body weight among different age groups.