Background: Reflective debriefing strategy is a form of active self-learning where nursing students use self-discovery through reflection on their performance that lead to increase academic achievement. Aim of the study: Assess effect of applying reflective debriefing strategy for practical nursing administration course on academic achievement for nursing students. Study design: A quasi-experimental design was used. Setting: The study was conducted at Nursing Administration department at Faculty of Nursing, Benha University. Study subjects: Systematic random sample of the fourth year nursing students (n=50). Data collection tools: Three tools were used I: Nursing student knowledge questionnaire regarding practical Nursing Administration course, II: Nursing students observational checklist regarding practical nursing administration course, Tool III: Retrospective audit of achievement. Results: The minority (6.0%) of the studied nursing students had good knowledge level regarding practical nursing administration course at pre-applying reflective debriefing strategy and improved to more than three quarters (82.0%) at post applying reflective debriefing strategy, the minority (6.0%) of the studied nursing students were had competent level regarding practical nursing administration course at pre-applying reflective debriefing strategy and improved to the majority (90.0%) at post applying reflective debriefing strategy, the majority (94.0%) of the studied nursing students had excellent level regarding academic achievement after applying reflective debriefing strategy.Conclusion: There was a highly statistically significant positive correlation among studied nursing students knowledge, skills regarding practical nursing administration course and academic achievement after applying reflective debriefing strategy. Recommendations: Integrating reflective debriefing strategy into the nursing curriculum as a teaching method in combination with traditional clinical teaching methods, integrating nursing students in reflective debriefing strategy discussions to increase academic achievement.