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410683

Predictive Value of Stress Hyperglycemia Ratio on Intracoronary Thrombus Burden in Patients with ST Segment Elevation Myocardial Infarction

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Last updated: 08 Feb 2025

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Abstract

Background: Primary percutaneous coronary intervention (PCI) is the recommended treatment for ST-segment elevation myocardial infarction (STEMI). Substantial coronary thrombus during primary PCI is associated with a poor prognosis. While stress hyperglycemia is common in STEMI patients, its association with intracoronary thrombus extent is uncertain. Patients and Methods: The study included 100 STEMI patients eligible for primary PCI within 12 hours of symptom onset. SHR was calculated by dividing admission glucose by the estimated average glucose derived from HbA1c. Intracoronary thrombus burden was angiographically assessed using the Thrombolysis in Myocardial Infarction (TIMI) thrombus grade scale. Patients with thrombus grades 1 to 3 were categorized as the small thrombus burden (STB) group, and those with grades 4 and 5 as the large thrombus burden (LTB) group. Results: SHR was significantly higher in the LTB group compared to the STB group (p=0.016), regardless of diabetic status. SHR demonstrated significant predictive value for LTB when the cut-off value exceeded 1.37, with a sensitivity of 67.24% and a specificity of 54.76%. Both univariate and multivariate analyses showed that LTB was independently predicted by SHR and admission blood glucose levels. No relationship was found between SHR and post-primary PCI TIMI flow grade or in-hospital clinical outcome. Conclusions: SHR and admission hyperglycemia were independent predictors for LTB incidence in STEMI patients.

DOI

10.21608/ejhm.2025.410683

Keywords

Stress hyperglycemia ratio, ST-Segment elevation myocardial infarction, Intracoronary Thrombus Burden

Volume

98

Article Issue

1

Related Issue

52551

Issue Date

2025-01-01

Receive Date

2025-02-07

Publish Date

2025-01-01

Page Start

713

Page End

719

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 98_Issue 1_Pages 713-719.pdf

PDF . 809.8kB

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https://ejhm.journals.ekb.eg/article_410683.html

Detail API

http://journals.ekb.eg?_action=service&article_code=410683

Order

105

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Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Predictive Value of Stress Hyperglycemia Ratio on Intracoronary Thrombus Burden in Patients with ST Segment Elevation Myocardial Infarction

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Article

Created At

08 Feb 2025