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410682

Hypo-Fractionation Radiotherapy in Breast Cancer Patients: Review Article

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Last updated: 08 Feb 2025

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Abstract

In breast carcinoma management, radiation therapy (RT) is a necessary management. The typical therapeutic regimen for RT to the breast involves administering 25 fractions of 2.0 Gy per day over a five-week period. Breast cancer is more suitable for greater fraction sizes than squamous carcinomas, according to datasupporting the use of fewer fractions of more than 2 Gy per day (hypo-fractionation). Consequently, it may exhibit similarly high fractionation sensitivity to the dose-limiting normal tissues, such as muscle, subcutaneous tissues, skin, and ribs. This article examins the literature that supports the hypo-fractionated radiation efficacy in breast cancer treatment, explore the radiobiological rationale that is unique to carcinomas of breast, and present a case for the regimen implementation of shorter, hypo-fractionated RT sessions when radiation administered on breast.

DOI

10.21608/ejhm.2025.410682

Keywords

Hypo-fractionation, breast cancer, Radiotherapy, conventional fractionation, radiobiology

Volume

98

Article Issue

1

Related Issue

52551

Issue Date

2025-01-01

Receive Date

2025-02-07

Publish Date

2025-01-01

Page Start

706

Page End

712

Print ISSN

1687-2002

Online ISSN

2090-7125

Article File

EJHM_Volume 98_Issue 1_Pages 706-712.pdf

PDF . 624.5kB

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https://ejhm.journals.ekb.eg/article_410682.html

Detail API

http://journals.ekb.eg?_action=service&article_code=410682

Order

104

Type

Original Article

Type Code

606

Publication Type

Journal

Publication Title

The Egyptian Journal of Hospital Medicine

Publication Link

https://ejhm.journals.ekb.eg/

MainTitle

Hypo-Fractionation Radiotherapy in Breast Cancer Patients: Review Article

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Type

Article

Created At

08 Feb 2025