The fogging technique is promising for improving humidification-dehumidification system efficiency and reducing power usage. This research presents an experimental study of a new water desalination system that utilizes a humidification-dehumidification approach. The system is enhanced by including renewable energy sources and a cooling system that integrates a fogging technique. The air is heated using an air conditioning condenser to improve its capacity for effective humidification. Additionally, the fogging system enhances the evaporation process of saline water with a salinity of 34000 ppm. An experimental study investigated the effect of different operational factors such as the mass flow rate ratio, feed water temperatures, and cooling water temperatures on the produced water salinity, desalinated water productivity, efficiency, and cost. The findings indicate that implementing the integrated fogging system has resulted in a higher gain-output ratio and improved desalinated water productivity. The maximum gain output ratio was 8.8 and water productivity was 25 kg/hr. Similarly, the produced water salinity has been lowered from 34000 to 2300 ppm, showing a positive outcome. The water production cost was 0.0088 ($/liter) for this integrated water desalination system. It is concluded that implementing the integrated fogging system has resulted in higher performance and improved desalinated water productivity.