Background: Despite being uncommon, biliary atresia (BA) ranks high among newborn liver diseases that cause mortality. There is a defect of Knowledge, Attitude, and Practice (KAP) about Biliary Atresia among general practitioners and pediatricians. We aimed to assess the knowledge, attitude, and practice of primary care physicians and pediatricians regarding biliary atresia by validating the biliary atresia questionnaire (BAQ).

Methods: We conducted a cross-sectional study from 2022 up to 2024 in primary healthcare units and the department of pediatrics among150 healthcare providers) General practitioners and pediatricians(. Data was collected using structured questionnaires filled through Google form questionnaire sheets from primary healthcare providers to assess their KAP about biliary atresia. The Google form questionnaire was directed to general practitioners and pediatricians all over Egypt.

Results: Most participants, 91.4%, had a good attitude towards biliary atresia. The best attitude was towards Lack of knowledge and awareness regarding BA helps in the high percentage of delayed diagnosis as the majority of participants agreed (agree 49.7% - strongly agree 36.4); the leading defective biliary atresia practice was observed among studied regarding using of Stool colored card as a screening tool during evaluation of possible direct hyperbilirubinemia (cholestasis) among newborns only 37.1%.

Conclusions: The baseline levels of knowledge regarding biliary atresia among pediatricians were mainly good, except for poor knowledge of the Ruta virus as a cause of biliary atresia. Also, the baseline attitude levels were good.

Keywords: Knowledge, Attitude, Practice, General Practitioners, Biliary Atresia