The Delftia acidovorans bacteria is an aerobic, Gram-negative, nonfermenting Bacillus bacterium. It is considered nonpathogenic bacterium for humans, commonly distributed through nature in water and plants and rarely it becomes pathogenic for human. For the first time a hospitalized man at age 70 who had been diagnosed with chronic emphysema by the physician was admitted to the microbiology lab for identification of the pathogen responsible for the emphysema. A pus specimen was cultured on the blood, MacConkey, and Chocolate agar by using the VITEK 2 system, which indicates that this bacterium is the main causative agent for emphysema. In this case report, Delftia acidovorans was isolated and found to be sensitive to some antibiotics, including Cefotaxime, Ceftazidim, Trimethoprim/sulfamethoxazole, Levofloxacin, Ciprofloxacin, Piperacillin/Tazobactam, Aztreonam, Imipenem, and Metropenem. This is the first case report of the isolation of Delftia acidovorans from pus in a hospitalized patient in Iraq, mainly in Duhok City. The isolation of D. acidovorans in the pus specimen from the hospitalized patient by culturing on the Blood agar, MacConkey agar, and Chocolate agar, indicates that this bacterium is the main causative agent for emphysema.