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407515

A Comprehensive Systematic Review of Glaucoma: Diagnosis, Management, and Emerging Trends in Artificial Intelligence

Article

Last updated: 08 Feb 2025

Subjects

-

Tags

Pharmaceutics and Drug Manufacturing.

Abstract

Glaucoma is a progressive and often asymptomatic condition that leads to irreversible vision loss if left untreated, earning it the label of "the silent thief of sight." Slow disease progression often results in a delayed diagnosis. Treatment approaches for glaucoma range from pharmacological interventions to laser therapies and surgical procedures with the primary goal of reducing intraocular pressure (IOP). This review examines the current landscape of glaucoma diagnosis and treatment, highlighting the role of newer drug delivery techniques, advancements in laser and surgical options, and emerging use of artificial intelligence (AI) for enhanced patient outcomes. AI has made impressive progress in the field of glaucoma in recent years, with various machine learning models applied to diagnose glaucoma based on fundus photographs and optical coherence tomography, promising earlier detection and better patient management.

The prognosis of glaucoma is highly dependent on the stage at which it is detected, and the extent of optic nerve damage at the time of diagnosis. Early detection significantly improves the outcome, with proper treatment able to slow or halt the disease progression. The prognosis is generally favorable as long as the patients strictly adhere to their prescribed treatment regimen.

By analyzing both traditional and innovative therapeutic approaches, this study highlights the importance of personalized and targeted treatments to maximize the efficacy of glaucoma management. The incorporation of emerging technologies, particularly AI, represents a promising direction for improving the accuracy of diagnoses and enhancing future treatment strategies.

DOI

10.21608/jpsdm.2025.327744.1023

Keywords

Optic Disk Photography, Confocal Scanning Laser Ophthalmoscopy, Scanning Laser Polarimetry AI in Ophthalmology, prognosis of glaucoma

Authors

First Name

Rehab

Last Name

Abdelmonem

MiddleName

-

Affiliation

Industrial Pharmacy Department, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, P.O. Box 77, Giza, Egypt

Email

rehab.abdelmonem@must.edu.eg

City

6th October

Orcid

0000-0002-2522-8082

First Name

Hussein

Last Name

F. Ibrahim

MiddleName

-

Affiliation

Faculty of Pharmacy, Alexandria University.

Email

hussienamer199@gmail.com

City

-

Orcid

-

First Name

Fatma

Last Name

Mostafa

MiddleName

-

Affiliation

Department of Biochemistry, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, Giza

Email

fatmaa.mostafa@must.edu.eg

City

-

Orcid

-

First Name

Mina

Last Name

Josef

MiddleName

-

Affiliation

Industrial Pharmacy Department, College of Pharmaceutical Sciences and Drug Manufacturing, Misr University for Science and Technology, P.O. Box 77,Giza, Egypt

Email

mina.azmy@must.edu.eg

City

6th October

Orcid

0000-0002-4487-2658

Volume

2

Article Issue

1

Related Issue

53305

Issue Date

2025-01-01

Receive Date

2024-10-22

Publish Date

2025-01-01

Page Start

47

Page End

69

Print ISSN

3009-6553

Online ISSN

3009-6677

Link

https://jpsdm.journals.ekb.eg/article_407515.html

Detail API

http://journals.ekb.eg?_action=service&article_code=407515

Order

407,515

Type

Review Articles.

Type Code

2,974

Publication Type

Journal

Publication Title

Journal of Pharmaceutical Sciences and Drug Manufacturing-Misr University for Science and Technology

Publication Link

https://jpsdm.journals.ekb.eg/

MainTitle

A Comprehensive Systematic Review of Glaucoma: Diagnosis, Management, and Emerging Trends in Artificial Intelligence

Details

Type

Article

Created At

01 Feb 2025