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Evaluation of the Halopitys incurvus algae essential oil as a wound-healing candidate: An animal study

Article

Last updated: 25 Feb 2025

Subjects

-

Tags

Pharmaceutical Chemistry

Abstract

The use of seaweed in medicine has been known since antiquity but remains limited. The skin is an organthat has essential roles for the good functioning of our body but also in the image we give to others. This study lies within the scope of the valorization of essential oil of Halopitys incurvus alga field as antioxidants and healing. The methods applied to measure the antioxidant activity were trapping of the free radicals by using the 1,1'-diphenyl-2-picrylhydrazyl (DPPH°); ferric reducing antioxidant power (FRAP): hydroxyl radical scavenging; production of substances reacting with thiobarbituric acid (TBARS) and the estimation of total phenolic content. For evaluation the healing activity we used induced surgical wounds in Wistar rats. The results obtained show that the essential oil of the red algae Halopitys incurvus has a very significant antioxidant activity with all the tests used, DPPH, FRAP, Hydroxyl radical, TBARS with the respective IC50 values 106.05 ± 0.41, 264.8 ± 0.28, 208.51 ± 0.85, 100 ± 91(μg/ml). Also we discovered a very important healing capacity on the wounds produced on the Wistar rats. The results obtained confirm a correlation between the phytochemical study, the antioxidant activity and the healing capacity that demonstrate the essential oil of the red algae Halopitys incurvus constitutes a reservoir of components with a very interesting effect in the healing process.

DOI

10.21608/ejchem.2024.146064.7177

Keywords

Keyword: Halopitys incurvus, essential oil, phytochemical study, antioxidant activity and healing capacity

Authors

First Name

Soukaina

Last Name

EL kafhi

MiddleName

-

Affiliation

Department of biology faculty of science Choaib Doukali el Jadida Morocco

Email

soukaina.kafhi@gmail.com

City

ELJADIDA

Orcid

-

First Name

Samira

Last Name

Khlifi

MiddleName

-

Affiliation

Department of biology, Faculty of sciences Chouaib Doukkali, Eljadida, Morocco.

Email

samkhlifi@hotmail.com

City

ELJADIDA

Orcid

-

Volume

68

Article Issue

1

Related Issue

53249

Issue Date

2025-01-01

Receive Date

2022-11-10

Publish Date

2025-01-01

Page Start

21

Page End

27

Print ISSN

0449-2285

Online ISSN

2357-0245

Link

https://ejchem.journals.ekb.eg/article_357582.html

Detail API

http://journals.ekb.eg?_action=service&article_code=357582

Order

357,582

Type

Original Article

Type Code

297

Publication Type

Journal

Publication Title

Egyptian Journal of Chemistry

Publication Link

https://ejchem.journals.ekb.eg/

MainTitle

Evaluation of the Halopitys incurvus algae essential oil as a wound-healing candidate: An animal study

Details

Type

Article

Created At

01 Feb 2025