Background: Medical students are subjected to various stressors throughout their training, which has a considerable impact on their physical and mental health, such stressors must be fully understood within a cultural context to tailor supportive strategies. A descriptive co-relational design was utilized to achieve the objective of the study. This study was conducted at Faculty of medicine Faculty of Medicine, Minia University. Methods of 150 students was selected from the previous setting chosen. Three tools were used for data collection (first tool): A structured interviewing questionnaire to assess socio-demographic characteristics of the students as age, gender, residence, and parent's education, (second tool): Medicine education stress scale (academic stress subscale), (third tool): Self-control scale. Results: There was a statistically significant relationship between academic stress and self-control among medical students. Conclusion: It was concluded that there was a highly statistically significant negative correlation between academic stress and self-control among faculty of medical students. Recommendations: Stress management techniques, behavioral therapy techniques, assertiveness training techniques, and mindfulness training should be given to the student to help them relieve their academic stress and disturbed levels of self-control.