Okra, Abelmoschus esculentus L. (Malvaceae) is one of the most important vegetable and cash crop in Egypt. The present study was conducted to determine the effect of Spinosad on the population trends of Aphis gossypii, Bemisia tabaci and Empoasca discipiens infesting okra in relation to some weather factors during 2022 and 2023 seasons at Sohag Governorate. Data indicated that Spinosad treatment reduced the number of the three studied pests and affected on their fluctuation trends in both seasons. Spinosad reduced A. gossypii, B. tabaci and E. discipiens by 67.53%, 62.80% and 50.37%, respectively, in 2022 season, and 64.66%, 66.99% and 51.31%, respectively, in 2023 season. For the parasitism of A. gossypii by Aphidius colemani, it is clear that the parasitism percentage decreased from 12.35% and 8.87% in control to 9.56% and 7.01% in Spinosad with reduction percentage of 22.64% and 21.00% in the two seasons, respectively. In case of weather factors, results showed that the temperature and relative humidity varied in their effect depending on factor, insect and season. However, it is clear that parasitoid showed highly positive significant effect on A. gossypii activity in both treated and untreated okra in the two seasons.