The study aims to discuss the applications of nanotechnology in architecture, especially in Office buildings. Nanotechnology is one of the most important modern applications that directly affect the characteristics and behavior of the smart materials used in the buildings, which have a direct impact on the use of materials in the internal and external
environments. There are many different applications of nanotechnology in Office buildings to achieve the greatest
efficiency such as (Carbon Nanotubes (C.N.T) - Temperature regulation: Phase change materials (PCMs) - Air purifying material - Vacuum insulation panels (VIPs) - Fire-proof) by selecting a set of examples of Office buildings that have
applied nanotechnology. To the strategy of nanotechnology applications in the Office room.