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406195

Platelet-albumin-bilirubin score for prediction of complications in cirrhotic patients with acute variceal bleeding

Article

Last updated: 20 Jan 2025

Subjects

-

Tags

Internal medicine ·

Abstract

Background:  Acute variceal bleeding as a cause of upper gastrointestinal tract hemorrhage is a serious problem that resulting in early death of cirrhotic patients. So, predicting the risk of early re-bleeding and death is crucial for preventing morbidity and mortality. Nowadays , there are multiple scoring systems with good prognostic power  have been developed, but there  is still a need  to find an easier and better scores that can be applied in clinical practice within each population and country. Aim: evaluation of the role of ALBI and PALBI scores as a prognostic tools in cirrhotic patients with variceal bleeding. Methodology: cross-sectional prospective study , done on patients admitted to Hepatology, Gastroenterology and Infectious diseases department at Beni-Suef University Hospital in Egypt who complained of acute onset of variceal bleeding. ALBI and PALBI were calculated and correlated with rates of hospital rebreeding and mortality.  Results: This study was done on 100 patients. The rates of first attack of bleeding, rebreeding and in-hospital mortality were 43 patients (43%), 37patients (37%) and 20 patients (20%). Age was a significant risk factor for in hospital morbidity and mortality (P= 0.008*) . Hb, WBCs, PLTs, Creatinine, liver enzymes (AST, ALT) and Bilirubin (T, D) had a statically significant relation to re-bleeding. Regarding hospital mortality,  ALBI , PALBI and MELD scores  have a better  prognostic value in prediction of mortality with  AUC  0.726, 0.798  and  0.750  respectively. Conclusion: ALBI, PALBI and MELD scores were helpful for prediction of hospital mortality in patients with variceal bleeding.

DOI

10.21608/ejmr.2024.277897.1591

Keywords

Cirrhosis, Albumin Bilirubin, Platelet albumin bilirubin, variceal bleeding

Authors

First Name

Asmaa

Last Name

Salama Sieddek

MiddleName

-

Affiliation

Lecturer of Hepatology, Gastroenterology and Infectious diseases. Beni-Suef University, Egypt

Email

asmaa.salama@med.bsu.edu.eg

City

-

Orcid

-

First Name

Walaa

Last Name

Mohamed sayed

MiddleName

-

Affiliation

Assistant lecturer of Hepatology, Gastroenterology and Infectious diseases, Faculty of Medicine, Beni Suef University, , Beni Suef, Egypt,

Email

wm9515886@gmail.com

City

-

Orcid

-

First Name

Shaymaa

Last Name

Nafady

MiddleName

-

Affiliation

Lecturer of Hepatology, Gastroenterology and Infectious diseases. Beni Suef University, Egypt

Email

shnafady@yahoo.com

City

-

Orcid

-

Volume

6

Article Issue

1

Related Issue

52942

Issue Date

2025-01-01

Receive Date

2024-03-18

Publish Date

2025-01-01

Print ISSN

2682-4396

Online ISSN

2682-440X

Link

https://ejmr.journals.ekb.eg/article_406195.html

Detail API

http://journals.ekb.eg?_action=service&article_code=406195

Order

406,195

Type

Original Article

Type Code

1,224

Publication Type

Journal

Publication Title

Egyptian Journal of Medical Research

Publication Link

https://ejmr.journals.ekb.eg/

MainTitle

Platelet-albumin-bilirubin score for prediction of complications in cirrhotic patients with acute variceal bleeding

Details

Type

Article

Created At

20 Jan 2025