Background: Depending on the kind of injury, its severity, and the area of the brain affected, traumatic brain injury can have a variety of health repercussions that may occasionally last for a long time or even be irreversible. Aim: The present study aimed to evaluate the effect of early designated exercise program on balance, mobility and risk for falling among traumatic brain injury patients.  Design: A quasi-experimental (pre/posttest) design was used in the present study. Settings:  The study was conducted in inpatient wards at neurological intensive care unit (ICU) and neuro-surgical unit at emergency Hospitals Mansoura University, Mansoura governorate, Egypt.  Subjects: A purposive sample of 40 adult patients with acute traumatic brain injury (TBI). Tools of data collection:  Data were collected using tool I: Structured patient's neurological assessment sheet; Tool II: Berg balance scale. Results: Severity of traumatic brain injury of studied patients has been decreased from (82.5%) for moderate degree and (7.5%) for sever cases pre implementation to (87.5%) cases with mild degree TBI post implementation. Total scores of Berg balance scale of the studied patients were improved from (39.05±7.75) pre implementation to (50.90±3.34) post implementation with highly significant difference in all items of Berg balance scale scores (<0.001). Conclusion: Early designated exercise program was effective to improve balance, mobility as well as reduced risk of falling among traumatic brain injury patients according to the total scores of Berg balance scale. Recommendation: carrying out additional research while paying close attention to offering program sessions one-on-one to patients in order to maximize program impact.