Different rice entries, of known sources, were planted. Rice Stem Borer (RSB) and Rice Leaf Miner (RLM) infestation was evaluated. Total protein, crude silica and fifteen amino acid contents were determined. The correlation between chemical contents and insect infestation showed certain results. Protein increased RSB infestation in most rice entries with posi‌tive correlation (r=0.45), while decreased RLM infestation in most rice entries with negative correlation (r=-0.77). Silica decreased infestation of both RSB and RLM and RLM with negative correlations (r= -0.13 and -0.23, respectively). Free amino acids showed different effects. Some of them decreased RSB infestation as alanine, glycine, histidine + arginine, aspartic+serine and valine, and some decreased RLM infestation as orni‌thine + lysine, histidine + arginine and methionine. Other amino acids in‌creased insect infestation. Japonica entries showed more resistance against RSB than indica entries and have less protein content, while the indica entries showed more resistance againt RLM insect and higher protein content. As so, the source plays role in host resistance . It can be concluded that chemical components may play an im-portant role in plant resistance, but is not the deterimental factor and other morphological, histological, and/or chemical factors share in plant resistance.