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405376

CINNAMON NANO PARTICLES (CNPs) AS FEED ADDITIVES ON RABBIT GROWTH PERFORMANCE, IMMUNITY, ANTIOXIDANT CAPACITY, AND RESISTANCE TO ESCHERICHIA COLI

Article

Last updated: 20 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Animal nutrition; Clinical Nutrition; Nutritional diseases

Abstract

The use of antibiotics in the poultry industry has been restricted. As a result, the phytogenic feed additives have been increasely utilized to serve this purpose, as well as for other benefits. This study aimed to investigate the effects of cinnamon nanoparticles (CNPs) on rabbit growth performance, immunity, serum biochemistry, blood hematology, cell histology, and protection against Escherichia coli O25.Therefore, sixty healthy weaned white New Zealand rabbits (35 days old) were separated into six equal groups. The rabbits were acquired from a private farm in Kafrelsheikh Governorate and acclimated for two weeks before the starting of the experiment. The rabbits groups were divided according to CNPs supplementation with or without antibiotic and experimental infection. According to our findings, the rabbits that received CNPs exhibited improved growth performance, P.M. lesions, bacterial re-isolation outcomes, and clinical symptoms. The hepatic and reno-protective effects of CNPs may be supported by decreases in the activities of serum ALT and AST and increases in the level of total protein and albumin, counts of total white blood cell and lymphocyte, and activities of antioxidant enzyme (SOD and CAT). The histopathological analysis showed that the positive control group had apparent pathological changes, such as interstitial nephritis, hepatic coagulative necrosis, and interstitial pneumonia with mononuclear cell infiltration. However, the superior effect was observed in the CNPs and streptomycin-treated group with milder to moderately altered tissue conditions. Thus, under current experimental conditions, dietary CNPs improved growth performance, antioxidant activity, and protection against experimental infection without pathological lesions.

DOI

10.21608/avmj.2025.320513.1399

Keywords

E. coli infection, Growth performance, health status, cinnamon nanoparticles (CNPs), Rabbits

Authors

First Name

GEHAN,

Last Name

ALi

MiddleName

I.E

Affiliation

Biochemistry, Nutritional Deficiency Diseases and Toxicology Unit, Kafrelsheikh Provincial Lab, Animal Health Research Institute, Agricultural Research Center (ARC), Giza, Egypt.

Email

gigi_doctor@yahoo.com

City

kafrelsheikh

Orcid

0009-0006-3236-6084

First Name

TAHOON,

Last Name

A.Y.

MiddleName

-

Affiliation

Poultry Diseases Unit, Kafrelsheikh Provincial Lab, Animal Health Research Institute, Agricultural Research Center (ARC), Giza, Egypt.

Email

abdelnaby@yahoo.com

City

kafrelsheikh

Orcid

-

First Name

NEHAL,

Last Name

NAENA

MiddleName

A.A.

Affiliation

Bacteriology Unit, Kafrelsheikh Provincial Lab, Animal Health Research Institute, Agricultural Research Center (ARC), Giza, Egypt.

Email

nehalali987@yahoo.com

City

kafrelsheikh

Orcid

-

First Name

EL-KEREDY

Last Name

ABEER

MiddleName

M.S.

Affiliation

Biochemistry, Nutritional Deficiency Diseases and Toxicology Unit, Kafrelsheikh Provincial Lab, Animal Health Research Institute, Agricultural Research Center (ARC), Giza, Egypt.

Email

abeershehata@yahoo.com

City

kafrelsheikh

Orcid

-

First Name

EMAN

Last Name

AL-SOKARY

MiddleName

T.

Affiliation

Biochemistry, Nutritional Deficiency Diseases and Toxicology Unit, Kafrelsheikh Provincial Lab, Animal Health Research Institute, Agricultural Research Center (ARC), Giza, Egypt.

Email

etawfek@yahoo.com

City

kafrelsheikh

Orcid

-

First Name

SHAIMAA

Last Name

ELBAZ

MiddleName

-

Affiliation

Biochemistry, Nutritional Deficiency Diseases and Toxicology Unit, Kafrelsheikh Provincial Lab, Animal Health Research Institute, Agricultural Research Center (ARC), Giza, Egypt.

Email

shsimaaelbaz@yahoo.com

City

kafrelsheikh

Orcid

-

First Name

SAMAH

Last Name

ABOU ASA

MiddleName

-

Affiliation

Faculty of Veterinary Medicine, Kafrelsheikh University, Pathology Department.

Email

samahabouasa@yahoo.com

City

-

Orcid

-

Volume

71

Article Issue

184

Related Issue

52949

Issue Date

2025-01-01

Receive Date

2024-09-12

Publish Date

2025-01-01

Page Start

608

Page End

634

Print ISSN

1012-5973

Online ISSN

2314-5226

Article File

AVMJ_Volume 71_Issue 184_Pages 608-634.pdf

PDF . 1.8MB

Link

https://avmj.journals.ekb.eg/article_405376.html

Detail API

http://journals.ekb.eg?_action=service&article_code=405376

Order

405,376

Type

Research article

Type Code

1,840

Publication Type

Journal

Publication Title

Assiut Veterinary Medical Journal

Publication Link

https://avmj.journals.ekb.eg/

MainTitle

CINNAMON NANO PARTICLES (CNPs) AS FEED ADDITIVES ON RABBIT GROWTH PERFORMANCE, IMMUNITY, ANTIOXIDANT CAPACITY, AND RESISTANCE TO ESCHERICHIA COLI

Details

Type

Article

Created At

20 Jan 2025