This study aimed to examine the relationship between online knowledge-sharing and innovative work behavior among academics in Egyptian universities. Employing a quantitative approach, the study gathered data through a self-administered questionnaire distributed to 386 academics across five Egyptian governmental universities. Data analysis and hypothesis testing were conducted with WarpPLS v.8 software specifically employing the partial least squares structural equation modeling (PLS-SEM) technique. The findings reveal a positive correlation between the two dimensions of online knowledge sharing (knowledge collecting and knowledge donating) and academic staff's innovative work behavior. Moreover, top management support was proven to partly moderate the relationship between online knowledge sharing (i.e., online knowledge collecting) and innovative work behavior. The study offers valuable insights into the factors influencing academics' online knowledge sharing and its impact on fostering innovation within Egyptian universities. By understanding this relationship, universities can develop and implement targeted strategies to promote the use of online knowledge-sharing tools and encourage academic staff's innovative work behaviors.