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404832

Evaluation of the Interleukin-8 and Interleukin12 Indices among Individuals Infected with Helicobacter pylori and Suffering from Gastric Ulcers

Article

Last updated: 09 Apr 2025

OverviewSimilar Items

Subjects

-

Tags

Clinical microbiology

Abstract

Background: Gastric ulcers, also known as peptic ulcers, are a common gastrointestinal condition characterized by the presence of sores or lesions in the lining of the stomach or the upper part of the small intestine. Objective: This study investigates the relation between interleukin-8 and interleukin-12 in individuals infected with Helicobacter pylori and suffering from gastric ulcers. Methodology: The study involved 30 healthy individuals and 30 individuals with Helicobacter pylori infection and gastric ulcers recruited between September 2023 and January 2024.  All individuals' serum levels were measured using the ELISA technique for detection of interleukin-8 and interleukin-12. Results: The serum levels of interleukin-8 and interleukin-12 were significantly higher (P<0.05) in patients than in healthy individuals. On the other hand, cases with gastric ulcer had significant higher (P<0.05) serum levels of IL-8 and IL-12 compared to cases only infected with H. pylori. Conclusion: In patients with stomach ulcers and H-pylori infection, IL8 and IL-12 levels were significantly higher than in controls, suggesting that these markers may be useful for diagnosis.

DOI

10.21608/ejmm.2025.346017.1407

Keywords

Gastric ulcer, Helicobacter pylori, Interleukins

Authors

First Name

Baneen

Last Name

Mohammed

MiddleName

S.

Affiliation

University of Kufa-Faculty of Science-Department of Biology-Iraq

Email

ba4321aa@gmail.com

City

-

Orcid

-

First Name

ِAhmed

Last Name

Aljanaby

MiddleName

A.J.

Affiliation

University of Kufa-Faculty of Science-Department of Biology-Iraq

Email

ahmedjaloob@gmail.com

City

-

Orcid

-

Volume

34

Article Issue

2

Related Issue

51523

Issue Date

2025-04-01

Receive Date

2024-12-19

Publish Date

2025-04-01

Page Start

195

Page End

199

Print ISSN

1110-2179

Online ISSN

2537-0979

Article File

EJMM_Volume 34_Issue 2_Pages 195-199.pdf

PDF . 203.1kB

Link

https://ejmm.journals.ekb.eg/article_404832.html

Detail API

http://journals.ekb.eg?_action=service&article_code=404832

Order

23

Type

New and original researches in the field of Microbiology.

Type Code

2,038

Publication Type

Journal

Publication Title

Egyptian Journal of Medical Microbiology

Publication Link

https://ejmm.journals.ekb.eg/

MainTitle

Evaluation of the Interleukin-8 and Interleukin12 Indices among Individuals Infected with Helicobacter pylori and Suffering from Gastric Ulcers

Details

Type

Article

Created At

20 Jan 2025