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404830

Clinical Correlates of Soluble sCD163 and IL9 in Patients with Chronic Kidney Disease and Lupus Nephritis

Article

Last updated: 09 Apr 2025

OverviewSimilar Items

Subjects

-

Tags

Clinical microbiology

Abstract

Background: Chronic kidney disease is a progressive condition characterized by the gradual deterioration of renal function, leading to the accumulation of waste products in the body. This condition affects over 800 million individuals globally with a disproportionate burden on older adults, women, racial minorities, and individuals with diabetes mellitus or hypertension. Objective: the aim of this works is to study the immunological role of cluster of differentiation163 and interleukin9 in patients with chronic kidney disease and lupus nephritis. Methodology:  From 1st August 2023 until the end of January 2024, 40 healthy participants and 80 patients with chronic kidney disease and lupus nephritis were enrolled in this study at AL-Najaf Hospital.  The ELISA test was used to test sCD163 and IL9 in each patients' blood. Results: Patients' serum levels of IL9 and sCD163 were substantially higher (P<0.05) than those of control participants. There was no appreciable variations in sCD163 and IL9 between cases with lupus nephritis and those with chronic renal disease. Conclusion: Our results proved that there was an important immunological role of sCD163 and IL9 in patients with chronic kidney disease and lupus nephritis.

DOI

10.21608/ejmm.2025.346014.1406

Keywords

biomarkers, Chronic Kidney Disease, Lupus nephritis, Interleukins

Authors

First Name

Ameer

Last Name

Mohammad

MiddleName

K.

Affiliation

Department of Biology, Faculty of Science, University of Kufa, Iraq

Email

ameerkareem238@gmail.com

City

-

Orcid

-

First Name

ِAhmed

Last Name

Aljanaby

MiddleName

A.J.

Affiliation

Department of Biology, Faculty of Science, University of Kufa, Iraq

Email

ahmedjaloob@gmail.com

City

-

Orcid

-

Volume

34

Article Issue

2

Related Issue

51523

Issue Date

2025-04-01

Receive Date

2024-12-19

Publish Date

2025-04-01

Page Start

183

Page End

187

Print ISSN

1110-2179

Online ISSN

2537-0979

Article File

EJMM_Volume 34_Issue 2_Pages 183-187.pdf

PDF . 202.2kB

Link

https://ejmm.journals.ekb.eg/article_404830.html

Detail API

http://journals.ekb.eg?_action=service&article_code=404830

Order

21

Type

New and original researches in the field of Microbiology.

Type Code

2,038

Publication Type

Journal

Publication Title

Egyptian Journal of Medical Microbiology

Publication Link

https://ejmm.journals.ekb.eg/

MainTitle

Clinical Correlates of Soluble sCD163 and IL9 in Patients with Chronic Kidney Disease and Lupus Nephritis

Details

Type

Article

Created At

20 Jan 2025