Vehicular Ad Hoc Network (VANET) is a new intelligent technology that includes communication between vehicles that are moving at high speed. It is used to establish a safer environment on the roads, reduce fuel consumption and pollution, or help the driver to discover services (shops, gas stations, etc.) on that street. All of this is intended for the safety and comfortability of the passengers while using their vehicles. Its target to obtain a spread continuous connectivity for vehicles, which can be achieved by either efficient vehicle-to-vehicle (V2V) or vehicle-to-roadside unit (V2RSU) communication. This paper aims to compare the average throughput, packet delivery ratio and packet loss ratio for AODV, AOMDV, DSDV, and DSR topology-based protocols. The results indicate that the best protocol for all metrics is AODV. For medium and high density, DSR is the worst.