This paper presents an applied element method-based model for the collapse analysis of reinforced concrete (RC) beam-column assemblages under middle column removal scenario. In Extreme Loading for Structures software (ELS), nonlinear constitutive material models are used for concrete and steel in joint with suitable solid and spring geometrical elements. For several validation studies, a comparison between the experimental and numerical crack patterns and failure modes is presented. All structure behavior stages till failure of specimens are simulated effectively by the presented models. This study highlights several behavior stages for beam column assemblages till the failure stage. The effect of seismic detailing, lap splice and bottom reinforcement ratio on the beam column assemblage behavior under middle column removal scenario, is also discussed and evaluated through the numerical investigation.