The piled raft system has proved to be a reasonable foundation system compared with the traditional pile foundation systems. However, there is a hesitation for considering the utilization of piled rafts on very loose sand underlain by inclined very soft soil due to limitations concerning insufficient bearing capacity and excessive settlement. Therefore, this study aims to describe the behavior of piled raft on very loose sand underlain by inclined soft clay layer varied between 3 m and 6 m using a 3D finite element approach. A series of numerical analysis was performed to study the behavior of the piled raft foundation system using various factors including raft thickness, pile length, and pile spacing, which are considered for an economical and effective design. The results showed that the length and spacing of piles might affect both bearing capacity and the settlement performance of the raft. In addition, increasing the pile length can decrease the settlement, but after reaching a certain length, the increase in pile length demonstrated the settlement tended to be insignificant. Therefore, to achieve an economic design, it is vital to consider the optimal pile length in the design of raft foundation model according to the allowable settlement.