Beta
ManageSearchChatDiscover
392008

Improved Subclinical Left Ventricular dysfunction by global longitudinal strain in Dyslipidemic Patients After Statin Therapy

Article

Last updated: 13 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

-

Abstract

Dyslipidemia is an important risk factor for cardiovascular diseases. Statin therapy is the principal treatment for dyslipidemia. Global longitudinal systolic strain (GLSS) is a reliable imaging technique used to identify subtle changes in the function of the left ventricle (LV), which often occur before significant impairment to LV function can be detected using the ejection fraction (EF). We aimed to assess subclinical structural myocardial abnormalities in dyslipidemic patients before and after statin therapy. The study compared global and segmental longitudinal systolic strain in thirty dyslipidemic patients with normal LVEF before and after 6 months of statin therapy and thirty healthy individuals. All participants underwent screening for lipid profile, conventional echocardiographic Doppler testing, and 2D speckle tracking. GLSS was impaired in dyslipedimic patients in comparison with control. This impairment was improved after 6 months of statin therapy. This suggests the presence of subclinical systolic dysfunction of the left ventricle, which improves with statins.

DOI

10.21608/bmfj.2024.310398.2160

Keywords

dyslipidemia, statin therapy, Strain imaging

Authors

First Name

Hanaa

Last Name

Abdelaziz

MiddleName

M M

Affiliation

Cardiovascular Medicine Department, Faculty of Medicine – Mansoura University, Mansoura, Daqahlya, Egypt.

Email

hanaa.mm.abdelaziz@mans.edu.eg

City

Mansoura

Orcid

0000-0001-5999-6621

First Name

Eslam

Last Name

Elmenyawy

MiddleName

Elsayed Mohamed

Affiliation

Cardiovascular Medicine Department, Faculty of Medicine, Suez University, Suez, Egypt

Email

eslam.elmenyawy@med.suezuni.edu.eg

City

Suez

Orcid

-

First Name

Hesham

Last Name

Waly

MiddleName

Mohammed Fathy

Affiliation

Cardiovascular Medicine Department, Faculty of Medicine – Mansoura University, Mansoura, Daqahlya, Egypt

Email

heshwaly@mans.edu.eg

City

Mansoura

Orcid

-

First Name

Abdul Razek

Last Name

Maaty

MiddleName

Abdul Lateef

Affiliation

Cardiovascular Medicine Department, Faculty of Medicine – Mansoura University, Mansoura, Daqahlya, Egypt.

Email

maatyforall@yahoo.com

City

Mansoura

Orcid

-

First Name

Hend

Last Name

Abu-El Fadl

MiddleName

Gamal

Affiliation

Diagnostic and Interventional Radiology Department, Faculty of Medicine – Mansoura University, Mansoura, Daqahlya, Egypt

Email

hendgamal@mans.edu.eg

City

Mansoura

Orcid

0000-0003-1621-679X

Volume

42

Article Issue

1

Related Issue

52766

Issue Date

2025-01-01

Receive Date

2024-08-06

Publish Date

2025-01-01

Page Start

198

Page End

212

Print ISSN

1110-208X

Online ISSN

2357-0016

Article File

BMFJ_Volume 42_Issue 1_Pages 198-212.pdf

PDF . 1.1MB

Link

https://bmfj.journals.ekb.eg/article_392008.html

Detail API

http://journals.ekb.eg?_action=service&article_code=392008

Order

20

Type

Original Article

Type Code

787

Publication Type

Journal

Publication Title

Benha Medical Journal

Publication Link

https://bmfj.journals.ekb.eg/

MainTitle

Improved Subclinical Left Ventricular dysfunction by global longitudinal strain in Dyslipidemic Patients After Statin Therapy

Details

Type

Article

Created At

13 Jan 2025