Background: The COVID-19 outbreak threatens society globally. Stress and depression are common. Electrophysiological, cognitive, psychological, and covid-19 disease assessments
Objectives: Assessment relationship between cognition, psychological and covid-19 disease.
Patients and methods: 30 patients had covid-19-positive PCR, and 25 healthy controls matched for Sex and Age. Electroencephalogram (EEG) assessed electrophysiological changes, cognitive functions were assessed using Trail Making Test (parts A and B) and Montreal Cognitive Assessment (MoCA), depression and anxiety were assessed using HAM D & A.
Results: No EEG changes after 1 month between cases and controls (p-value=0.099) and after 3 months (p-value=0.293).Follow, neither cases nor controls has EEG changes(p-value=0.630,1.0).Cases and controls differ in trail A(p-value=0.003) after month while after 3 months(p-value=0.123). In the cases, trail A after 1 month is different from trail A after 3 months(p-value=0.001). In controls, trail A after 1 month and 3 months is identical(p-value=0.428). Trail B shows no significant difference between cases and controls after 1 and 3 months(p-value=0.170,0.428)
Cases and controls differ in 1-month MoCA(p-value=0.001). Cases and controls have similar MoCA after 3 months (p-value=0.917). Repeat MoCA after 3 months differs statistically(p-value=0.001,0.896). HAM-A statistically differs between cases and controls after 1 month(p-value=0.005), but not after 3 months(p-value=0.133). Cases and controls differ for HAM A within 1 month and after 3 months (p-value=0.001,0.048). After 1 month, HAM D cases and controls differ (p-value=0.249,0.753).follow cases and controls identical (p-value=0.006,0.188)
Conclusion: Our study shows that SARS-CoV-2 impairs healthcare workers cognition and psyche.