To invetigate the effect of compost, mineral and bio- fertilization on yield and quality of sunflower cv giza120 under soil as affected by salinity, in this respect the two experiments was carried out at the Experimental Farm, Faculty of Agriculture, Saba Basha, Alexandria University, Alexandria Governorate, Egypt, during the two summer seasons of 2023 and 2024. This experiment was laid out in split plot design with three replications in both seasons. the compost fertilizer treatments are in the main plots, and the bio and mineral fertilization treatments for (nitrogen, phosphorus, and potassium) are distributed randomly in the sub plots. The obtained results showed that significant effects of compost manure, bio-mineral fertilization, and interaction between these two factors on yield characters of sunflowers, where the use of 1.5 tons per fed of compost, when paired with 50% of the recommended dosage of Mineral NPK and the bio-inoculation, resulted in significant improvements in the yield, as well as the various yield components and the seed quality of sunflower under the study conditions.