Financial inclusion is a crucial concept that ensures all members of the economy have access to formal financial systems and services, promoting economic growth and sustainability. The Middle East and North Africa (MENA) region has limited financial access, making financial inclusion a high priority to promote economic growth and development. This paper investigates the impact of financial inclusion on real GDP growth rate in the (MENA) region over the period from 2004 to 2022. Despite the significance of financial inclusion in promoting economic development, there is a lack of literature on this topic, particularly in the MENA region. The study aims to contribute to the existing literature by presenting the development of Financial inclusion in MENA region during the period (2004-2022), and examining the relationship between financial inclusion and real GDP growth rate in the MENA region. The chosen econometric approach is a linear regression performed on a set of time series data on the dependent variable economic growth and the independent variables of financial inclusion in the MENA region from 2004 to 2022 using OLS method. Our findings suggest that financial inclusion has a positive impact on real GDP growth rate in the MENA region, highlighting the importance of financial inclusion in promoting economic development in this region. The study also identifies factors that may help expand financial inclusion in the MENA region, such as improving access to financial products and services and increasing financial literacy.