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402814

Enhancing Periapical Healing in Endodontic Retreatment Cases: A Clinical Comparative Study Comparing Nano-Hydroxyapatite alone and combined with PRF.

Article

Last updated: 07 Jan 2025

Subjects

-

Tags

Endodontics

Abstract

Aim: This study aims to assess bone healing after periapical surgery using nHA and nHA+PRF.
Methods: Sixteen patients with periapical lesions in upper or lower anterior teeth with failed endodontic treatments were included. Teeth were divided into two groups of eight. All teeth were retreated in two visits. During the initial visit, the existing root canal filling was removed using ProTaper retreatment files (Dentsply Sirona®). Subsequently, the root canal was irrigated with a 2.5% sodium hypochlorite solution. Following irrigation, the canal was thoroughly dried and filled with a Bi-mix antibiotic paste composed of metronidazole and ciprofloxacin. During the second visit, canals were obturated with gutta-percha and sealer, followed by apicoectomy and root-end filling with MTA. In Group 1; nanohydroxyapatite (nHA) powder was packed into the bony periapical cavity. In Group 2, a mixture of nanohydroxyapatite (nHA) and platelet-rich fibrin (PRF) was packed into the bony periapical cavity. Follow-up visits were scheduled at 1, 3, and 6 months postoperatively for clinical and radiological assessments. Results: At one month follow up, the nHA and nHA+PRF groups showed significantly greater reduction in lesion size. No significant differences were observed between the two groups either at three or six months. Conclusion: nHA+PRF accelerated early bone regeneration compared to nHA alone

DOI

10.21608/edj.2024.338255.3270

Keywords

Periapical pathosis, bone healing, nano-hydroxyapatite, PRF, retreatment

Authors

First Name

Amira

Last Name

ElKholly

MiddleName

Mohammed

Affiliation

Lecturer of Endodontics , Faculty of Oral and Dental Medicine MTI University.

Email

dr.amiraelkholly@yahoo.com

City

Cairo,Egypt

Orcid

0000-0002-0296-0086

First Name

Maged

Last Name

Negm

MiddleName

-

Affiliation

Department of Endodontics, Faculty of Dentistry, Cairo University, Giza, Egypt;

Email

maged.negm@yahoo.com

City

Cairo,Egypt

Orcid

0000-0002-0091-043X

First Name

Reham

Last Name

Hassan

MiddleName

-

Affiliation

Department of Endodontics, Faculty of Dentistry, Egyptian-Russian University, Badr City, Egypt.

Email

reham-hassan@live.com

City

Minia

Orcid

0000-0003-2610-7159

First Name

Nada

Last Name

Mustafa Kamel

MiddleName

Omar

Affiliation

Associate Researcher professor of Endodontics, Restorative and Dental Materials Department, National Research Centre, Dokki, Giza, Egypt. - Associate professor of Endodontics, New Giza university, Egypt

Email

nadaomar25@hotmail.com

City

Cairo

Orcid

0000-0002-0091-043X

Volume

71

Article Issue

1

Related Issue

52725

Issue Date

2025-01-01

Receive Date

2024-11-21

Publish Date

2025-01-01

Page Start

957

Page End

967

Print ISSN

0070-9484

Online ISSN

2090-2360

Link

https://edj.journals.ekb.eg/article_402814.html

Detail API

http://journals.ekb.eg?_action=service&article_code=402814

Order

402,814

Type

Original Article

Type Code

254

Publication Type

Journal

Publication Title

Egyptian Dental Journal

Publication Link

https://edj.journals.ekb.eg/

MainTitle

Enhancing Periapical Healing in Endodontic Retreatment Cases: A Clinical Comparative Study Comparing Nano-Hydroxyapatite alone and combined with PRF.

Details

Type

Article

Created At

07 Jan 2025