Background: According to the Scottish Guideline, a chronic venous leg ulcer is an open lesion that develops in the presence of venous illness between the knee and ankle joints and does not heal after at least four weeks. Venous leg ulcers (VLUs) make up 70% of all leg ulcers and are thought to affect 1% of the population, with an incidence that rises with age, according to a cross-sectional research done on a random sample in Edinburgh.
Aim of the Work: To evaluate the efficacy of injection sclerotherapy of incompetent perforators in the healing of venous leg ulcers.
Patients and Methods: This study was conducted on 50 patients with chronic venous leg ulcers that had been presented at least four weeks ago. To evaluate the clinical efficacy of Duplex-guided foam sclerotherapy with compression therapy in comparison with compression therapy alone, we divided the patients with randomization into two groups. Group A was conservatively managed by a four-layer compression bandage and Group B was managed by the application of duplex-guided injection sclerotherapy and a four-layer compression bandage.
Results: Our research indicates a statistically significant positive association between the ulcer's duration, its surface area, and the amount of time it takes to heal completely. Only the ulcer surface area at the beginning of therapy was substantially connected with the period of full healing on linear regression analysis of covariates strongly correlated with it (β=1.031, p<0.001).
Conclusion: With just 45 minutes of work and no recovery period, patients undergoing duplex-guided sclerotherapy can return home from an outpatient clinic following a straightforward operation that requires neither hospitalization nor anesthesia. This is the first-line therapy for venous ulcers and is better than compression alone because of the relatively short healing time and clear results.