Climate change is a major driver of change in the agricultural sector, significantly impacting crop yields. This necessitates a comprehensive understanding of the effects of climate change on agricultural production and the development of strategies to mitigate its impacts. Ismailia Governorate, renowned for its diverse fruit cultivation, particularly mangoes, serves as a significant case study. This research aims to investigate the influence of climatic factors on mango yield in Ismailia Governorate during the period )2007-2022(. To achieve this objective, the study employed descriptive and quantitative statistical analysis of the data. The results revealed that increasing maximum temperature in August and minimum temperature in November led to a decline in yield. Additionally, higher relative humidity in May and August negatively impacted yield, while increased rainfall in November positively correlated with yield. Overall, the study found that climatic factors had a detrimental effect on mango yield during the study period. Based on these findings, the study recommends improving irrigation management during hot periods, strengthening supplementary irrigation programs to compensate for rainfall deficits in dry years, and implementing measures to mitigate high temperatures on fruits, such as fruit covering.