Background:  Diabetes mellitus (DM) represents a chronic metabolic condition marked by elevated blood glucose levels, due to defects in the release of insulin, its action, or both. DM is frequently linked to microvascular as well as macrovascular complications. Autonomic neuropathy presents with clinical symptoms such as hypoglycemia inattention, orthostatic low blood pressure, constipation, diarrhea, erection problems, along with neurogenic bladder. Aim of the study:  This study aimed to inspect the impact of interval versus continuous training on cardiovascular autonomic neuropathy (CAN) in type II diabetes mellitus. Methods: Sixty diabetic patients suffering from autonomic neuropathy, patients had been randomized into two groups equivalent in number, the study group (group A) as well as the control group (group B). Group (A) involved 30 diabetic patients who were treated by high intensity interval training. Group (B) involved 30 diabetic patients who were treated by moderate intensity continuous training. Heart rate variability (HRV) response, beat to beat variation with deep breathing and HRV with standing are the variables that were examined. The variability of blood pressure (VBP), quality of life (QoL), and reaction to standing, as well as hand grip blood pressure (DBP), as well as systolic blood pressure (SBP). Results: Following the treatment, a statistically significant difference was detected among the study and control groups on quality of life questionnaires, hemoglobin A1c% (HbA1c), blood pressure variability, in addition to heart rate variability. Conclusion: Practicing of interval training and continuous training had an effect on heart rate variability, blood pressure variability, HbA1c% and quality of life questionnaire but the interval training had more significant effect.