Objective: In our study we were focusing on treatment of ulcers in the lateral border of the tongue caused by repeated trauma and Temporomandibular joints (TMJ) subluxation. Moreover, we compared the results among non-syndromic patients (normal patients) versus syndromic patients (Ehlers-Danlos syndrome (EDS)).
Methods: This clinical, interventional, prospective, and randomized controlled study was carried out on individual chosen from the outpatient clinic. The study has been performed on 20 patients divided into two groups equally, Group I (control group) consisted of 10 normal patients had tongue ulceration and TMJ subluxation (4 males and 6 females). Group II (study group) consisted of 10 patients had tongue ulceration and TMJ subluxation with Ehler-Danlos syndrome (4 males and 6 females).
Results: After one day, group I showed a significant reduced pain score contrasted to group II (P-value = 0.015). After two days, group I revealed a significantly reduced pain score contrasted to group II (P-value = 0.012). After seven days, group I revealed a statistically significantly reduced pain score contrasted to group II (P-value = 0.071). A significant reduction in the diameter in group I in a shorter period contrasted to group II (P-value = 0.005).
Conclusion: low level laser therapy is an effective tool for management of tongue ulcer and intrarticular injection of auotologous blood is a magic choice for management of temporomandibular joint subluxation. However, non- syndromic normal patients showed marked and rapid improvement more than patients with Ehler-Danols syndrome.