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401373

Studies on Candida albicans causing vaginal and urinary tract inflammation: Prevalence, antifungal resistance, and natural product susceptibility

Article

Last updated: 01 Feb 2025

Subjects

-

Tags

Antimicrobials

Abstract

Antifungal resistance in Candida albicans is one of the most harmful microorganisms that can cause inflammation in the vaginal and urinary tracts. To get around this problem, we tested how well some natural products worked against C. albicans. This study focused on isolating, identifying, studying the prevalence, and the susceptibility of Candida to some natural products. After isolation on specific media, we carried out morphological and biochemical identification of the recovered Candida isolates. We then estimated the antifungal resistance of the isolates against antifungal substances and their sensitivity to apple cider vinegar, garlic, lavender, coconut, and tea tree oils. We obtained only twelve Candida isolates out of fifty urine samples and vaginal swabs. The biochemical identification revealed that all isolates were Candida spp. The most antifungal-resistant isolates have an estimated ITS gene. After that, the susceptibility of six isolates to apple cider vinegar, tea tree oil, coconut oil, garlic oil, and lavender oil revealed the sensitivity of Candida to tested products. Finally, the ITS2 gene sequencing results confirmed the identification of C. albicans MS24 and C. albicans MS44 respectively. Our study concluded that C. albicans is considered one of the most common causes of vaginal and urinary tract inflammation. Also, natural products, especially tea tree oil and apple cider vinegar, have excellent antifungal activity against both C. albicans MS24 and MS44 respectively.

DOI

10.21608/mb.2024.325202.1185

Keywords

apple cider vinegar, C. albicans MS24 and MS44, Coconut oil, Egypt, garlic oil, lavender oil, Tea tree oil

Authors

First Name

Hussein

Last Name

Salama

MiddleName

Samir

Affiliation

Botany and Microbiology Department, Faculty of Science, Menoufia University, Egypt.

Email

husseinsalama@science.menofia.edu.eg

City

Menoufia

Orcid

-

First Name

Mohamed

Last Name

Shaaban

MiddleName

T.

Affiliation

Botany and Microbiology Department, Faculty of Science, Menoufia University, Egypt.

Email

mhdtawfiek@gmail.com

City

Menoufia

Orcid

-

First Name

Aymen

Last Name

Dawood

MiddleName

S.

Affiliation

Obstetrics and Gynecology Department, Faculty of Medicine, Tanta University, Egypt.

Email

aymen.dawood@med.tanta.edu.eg

City

Menoufia

Orcid

-

First Name

Azza

Last Name

Soliman

MiddleName

S.

Affiliation

Botany and Microbiology Department, Faculty of Science, Menoufia University, Egypt.

Email

azzamicr@yahoo.com

City

Menoufia

Orcid

-

First Name

Mohamed

Last Name

Shaheen

MiddleName

N.

Affiliation

Botany and Microbiology Department, Faculty of Science, Menoufia University, Egypt.

Email

mazenstar1999@gmail.com

City

Menoufia

Orcid

-

Volume

9

Article Issue

2

Related Issue

49870

Issue Date

2024-12-01

Receive Date

2024-10-01

Publish Date

2024-12-30

Page Start

189

Page End

194

Print ISSN

2357-0326

Online ISSN

2357-0334

Link

https://mb.journals.ekb.eg/article_401373.html

Detail API

http://journals.ekb.eg?_action=service&article_code=401373

Order

18

Type

Original Article

Type Code

502

Publication Type

Journal

Publication Title

Microbial Biosystems

Publication Link

https://mb.journals.ekb.eg/

MainTitle

Studies on Candida albicans causing vaginal and urinary tract inflammation: Prevalence, antifungal resistance, and natural product susceptibility

Details

Type

Article

Created At

07 Jan 2025