In the recent years natural dyes are using in textile dyeing. The main advantage of using natural dyes rather than synthetic dyes is low toxicity, it is biodegradable and waste water doesn't cause environmental hazards. Aqueous extraction of hazelnut shell is used in dyeing for cotton fabrics. Two different salts are used as mordant (Aluminum Sulphate and Copper Sulphate,). The aqueous extraction of hazelnut shell is prepared with three different concentrations (100,150 and 200 ml/l) to dye cotton fabrics. Some Investigations such as fastness properties (wash, rubbing and perspiration were done for natural extract dyed cotton, Scanning Electron Microscope (SEM) and antimicrobial activity. The highest wash fastness is recorded by Copper mordant (5 g/l) for 20 ml/l dye concentration. Antibacterial activity was evaluated for dyed fabrics and compared with Ag NPs treated fabrics. Hazelnuts shells aqueous extract dyed fabrics achieved superior antibacterial effects against both Staphylococcus aureus, and Escherichia coli. In general, dyed cotton fabrics with hazelnut shell extract showed superior antibacterial effects against S. Aureus. The antibacterial activity of dyed fabrics showed superior antibacterial efficiency than Silver coated fabrics. SEM for both hazelnut shells dyed cotton and silver nanoparticles coated cotton fabrics are performed. By using virtual 3D fashion design program, nine proposed designs of active wear for physical exercises and hospital uniforms are executed.