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401202

Indicators of the Need for Intensive Care Unit Admission in Patients Acutely Exposed to Corrosive Substances with Concern to Endoscopic Assessment, Tanta University Poison Contro

Article

Last updated: 30 Dec 2024

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Abstract

Background: Acute corrosive poisoning constitutes a significant health concern, characterized by a considerable incidence of severe morbidity and mortality. Aim of the work: This study aimed to identify patterns, potential indicators for the need for intensive care unit (ICU) admission in patients acutely exposed to corrosive substances, and endoscopic findings in patients who developed strictures. Patients and methods: This cross-section study included 70 patients with acute corrosive poisoning admitted to Tanta University Poison Control Center, Egypt, between September 2023 and September 2024. Patients were categorized into ICU-admitted patients and non-ICU-admitted patients. Outcomes were monitored and a gastroendoscopist followed the patients for 3 months. Results: The prevalence of corrosive poisoning was 7.9 % of all poisoned patients while the incidence of ICU admission was 18.6 % of all acute corrosive poisoning. Tachycardia, hypotension, vomiting, respiratory distress, hematemesis, pharyngeal involvement, need for endotracheal intubation, mechanical ventilation, tracheostomy, esophageal stricture, and surgical intervention were significantly high in ICU-admitted patients. In univariate analysis, age, hypotension, vomiting, hematemesis, esophageal stricture, and pharyngeal involvement were significant indicators for ICU admission. In multivariate analysis, esophageal stricture was a significant late indicator of the need for ICU admission. Furthermore, pulse rate, systolic, diastolic and temperature were the most reliable indicators for ICU admission. Conclusions: Patients presenting with vomiting, hematemesis, tachycardia, hypotension, and fever with late presentation of stricture are significant indicators of ICU admission. The incidence of esophageal and/or gastric strictures was 17.1% of the corrosive patients. Upper gastrointestinal endoscopic dilatation is an effective one month post-corrosive exposure.

DOI

10.21608/esctj.2024.343263.1077

Keywords

corrosive poisoning, Intensive Care Unit, Indicator, stricture, Endoscope

Authors

First Name

Alshaimma

Last Name

Elmansy

MiddleName

-

Affiliation

Forensic Medicine and Clinical Toxicology department, Faculty of Medicine, Tanta University, Egypt

Email

alshaimmaelmansy@gmail.com

City

-

Orcid

0000-0003-4273-8030

First Name

Fatma

Last Name

Sobeeh

MiddleName

Gaber

Affiliation

Forensic Medicine and Clinical Toxicology Department, Faculty of Medicine, Tanta University, Egypt.

Email

fatma.sobeeh@med.tanta.edu.eg

City

-

Orcid

-

First Name

Norhan

Last Name

AbuoHashish

MiddleName

Ahmed

Affiliation

Pharmacology Department, Faculty of Medicine, Tanta University, Egypt.

Email

nourhan.abohashesh@med.tanta.edu.eg

City

-

Orcid

0000-0002-4814-8421

First Name

Amany

Last Name

Dwidar

MiddleName

M

Affiliation

Gastroenterology and Hepatology Unit, Internal Medicine Department, Faculty of Medicine, Tanta University, Egypt.

Email

amany_dwidar20@yahoo.com

City

-

Orcid

-

First Name

Aliaa

Last Name

Hodeib

MiddleName

Abd Elhakam

Affiliation

Forensic Medicine and Clinical Toxicology Department, Faculty of Medicine, Tanta University, Egypt.

Email

aliaa.hodeib@med.tanta.edu.eg

City

-

Orcid

0000-0003-2504-546x

Volume

12

Article Issue

2

Related Issue

51764

Issue Date

2024-12-01

Receive Date

2024-12-09

Publish Date

2024-12-01

Page Start

172

Page End

190

Print ISSN

2356-6515

Online ISSN

2356-6523

Link

https://esctj.journals.ekb.eg/article_401202.html

Detail API

https://esctj.journals.ekb.eg/service?article_code=401202

Order

401,202

Type

Original Article

Type Code

1,098

Publication Type

Journal

Publication Title

Egyptian Society of Clinical Toxicology Journal

Publication Link

https://esctj.journals.ekb.eg/

MainTitle

Indicators of the Need for Intensive Care Unit Admission in Patients Acutely Exposed to Corrosive Substances with Concern to Endoscopic Assessment, Tanta University Poison Control Center, Egypt

Details

Type

Article

Created At

30 Dec 2024