Introduction: Osseo-integrated dental implants were traditionally load-free for up to six months while they healed. Patients usually feel dissatisfied with the long loading times. Several studies have been conducted to improve osseointegration, decrease loading time, and increase patient satisfaction.
Objectives: This study aimed to evaluate and compare both clinically and radiographically the effect of hyaluronic acid (HA) versus Titanium-Platelet Rich Fibrin (T-PRF) in enhancing osseointegration around anterior maxillary dental implants.
Materials and Methods: Twelve patients with extracted maxillary anterior teeth treated using 16 implants allocated into two groups; the study group was treated using delayed implant placement with hyaluronic acid as a bioactive coating, and the control group was treated using delayed implant placement with Titanium-Platelet Rich Fibrin as a bioactive coating. The patients were clinically evaluated at immediate postoperative and three months for implant stability. They were also evaluated radiographically at immediate postoperative, three, and six months for peri-implant bone density and crestal bone loss.
Results: There was no significant difference between the Hyaluronic acid group and the Titanium Platelet-Rich Fibrin groups regarding implant stability, crestal bone loss, and bone density.
Conclusions: According to the results of our study, it was concluded that Both HA and T-PRF are equally beneficial in enhancing implant stability, peri-implant bone formation, and osseointegration.