Beta
309612

A COMPARATIVE STUDY BETWEEN THE EFFECT OF PLATELET RICH FIBRIN AND CONCENTRATED GROWTH FACTORS ON OSSEOINTEGRATION OF IMMEDIATE IMPLANTS (A RANDOMIZED CLINICAL TRIAL)

Article

Last updated: 30 Dec 2024

Subjects

-

Tags

Oral and maxillofacial surgery

Abstract

Background: A lot of studies covered the use of growth factor-containing products as enhancers of osseointegration. Concentrated growth factors or CGF is a third generation platelet concentrate that is used to improve osseointegration of implants.
Aim of the study: to compare the effect of CGF on implant stability, bone density, and the horizontal dimension of the bone adjacent to the implant to that of platelet rich fibrin (PRF).
Material and methods: Fourteen participants with mandibular premolars that needed extraction and replaced immediately were assigned into two groups; a study group and a control group. A CGF membrane was laid in the implant osteotomies of the study group while a platelet-rich fibrin (PRF) membrane was placed in the osteotomies of the control group. The space in between the socket and the implant was filled with bone graft. To assess implant stability, a resonance frequency analysis (RFA) was performed immediately. After one week and after three months, a follow-up RFA was conducted. Preoperatively, directly after surgery, and three months afterwards, cone beam computed tomography (CBCT) was performed.
Results: Implant stability and bone density improved significantly in both groups after three months with no significant change in the horizontal dimension of bone for both groups. While higher implant stability and bone density readings were recorded in the CGF group, there was no change between the two groups that had statistical significance.
Conclusion: CGF enhances osseointegration more than PRF when evaluated radiographically and with resonance frequency analysis but with no statistical significance.

DOI

10.21608/adjalexu.2022.136173.1272

Keywords

Dental implants, growth factors, osseointegration, osteogenesis, Wound healing

Authors

First Name

Shady

Last Name

Khalifah

MiddleName

Abdelfattah

Affiliation

Department of oral and maxillofacial surgery, faculty of dentistry, alexandria university, alexandria, egypt

Email

shady.5alifah@gmail.com

City

Alexandria

Orcid

-

First Name

Marwa

Last Name

Noureldin

MiddleName

-

Affiliation

Department of Oral and Maxillofacial Surgery, Faculty of Dentistry, Alexandria University, Egypt

Email

drmarwagamal23@gmail.com

City

-

Orcid

0000-0003-3532-9685

First Name

Moustafa

Last Name

Eldibany

MiddleName

-

Affiliation

Professor of Oral and Maxillofacial Surgery, Conservative Dentistry, Faculty of Dentistry, Alexandria University, Alexandria, Egypt.

Email

eldibany@hotmail.com

City

Alexandria

Orcid

-

Volume

48

Article Issue

2

Related Issue

42602

Issue Date

2023-08-01

Receive Date

2022-05-07

Publish Date

2023-08-01

Page Start

39

Page End

45

Print ISSN

1110-015X

Online ISSN

2536-9156

Link

https://adjalexu.journals.ekb.eg/article_309612.html

Detail API

https://adjalexu.journals.ekb.eg/service?article_code=309612

Order

6

Type

Original Article

Type Code

1,057

Publication Type

Journal

Publication Title

Alexandria Dental Journal

Publication Link

https://adjalexu.journals.ekb.eg/

MainTitle

A COMPARATIVE STUDY BETWEEN THE EFFECT OF PLATELET RICH FIBRIN AND CONCENTRATED GROWTH FACTORS ON OSSEOINTEGRATION OF IMMEDIATE IMPLANTS (A RANDOMIZED CLINICAL TRIAL)

Details

Type

Article

Created At

30 Dec 2024