To study the efficacy of inactivated BVD virus for protection of the Baladi sheep against pestivirus infection (Border disease), BVD­antibody free twelve Iambs were immunized with two doses of the locally prepared BVD, IBR and P1-3 combined inactivated vaccine (Pneu­mo-3 vaccine) 2 weeks apart. Challenge test was done one month after the first inoculation. The vaccine evoked resistance against the chal­lenge with virulent BVD virus, and a protective level of antibodies per­sisted up to the 6th month after vaccination.