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400508

Prevalence of Regular Long-Acting Penicillin Administration as a Prophylaxis against Rheumatic Fever among Ismailia District Students Aged between 5–15 Years

Article

Last updated: 04 Jan 2025

OverviewSimilar Items

Subjects

-

Tags

Clinical Research (Medical)

Abstract

Background:Acute rheumatic fever (ARF) is a delayed sequela of streptococcal pharyngitis that involves many body systems. Rheumatic heart disease (RHD) is a serious health problem that leads to long-term morbidity and mortality. Intramuscular Long-acting penicillin (LAP) is the most effective antimicrobial agent in secondary prevention of RF, yet the overdiagnosis and unindicated use of LAP puts the children in avoidable hazards. Aim: To assess the non-indicated long-term use of long-acting penicillin as a prophylaxis against rheumatic fever among Ismailia district students. Subjects & Methods: This descriptive survey included 2180 students aged between 6 – 15 years in Ismailia government urban schools between October 2022 and April 2023. The children had comprehensive history taking, and those who reported LAP administration were asked for their previous investigations. Results: Twenty-one students (1%) reported LAP administration as prophylaxis of ARF. Only 7 students had definite ARF based on the Jones criteria. Six students (0.28%) had evidence of chronic RHD. Ten students discontinued the injections, 4 of them were against medical advice. Conclusions: There is a high prevalence of unindicated use of long-acting penicillin among basic education students due to overdiagnosis of ARF.Also, the criteria of diagnosis and regimen of treatment were variable.
 

DOI

10.21608/scumj.2025.400508

Keywords

Rheumatic Heart Disease, Arthritis, Basic-Education Students, Penicillin G Benzathine

Authors

First Name

Esraa

Last Name

Desouky

MiddleName

-

Affiliation

Department of Pediatrics and Neonatology, Faculty of Medicine, Suez Canal University, Egypt.

Email

esraadesouky1@gmail.com

City

-

Orcid

-

First Name

Mohammad E.

Last Name

Tawfik

MiddleName

-

Affiliation

Department of Pediatrics and Neonatology, Faculty of Medicine, Suez Canal University, Egypt.

Email

-

City

-

Orcid

-

First Name

Yasmine G.

Last Name

Mohamed

MiddleName

-

Affiliation

Department of Pediatrics and Neonatology, Faculty of Medicine, Suez Canal University, Egypt.

Email

-

City

-

Orcid

-

First Name

Ayman F.

Last Name

Sabry

MiddleName

-

Affiliation

Department of Pediatrics and Neonatology, Faculty of Medicine, Suez Canal University, Egypt.

Email

-

City

-

Orcid

-

Volume

28

Article Issue

1

Related Issue

52425

Issue Date

2025-01-01

Receive Date

2024-12-28

Publish Date

2025-01-01

Page Start

8

Page End

15

Print ISSN

1110-6999

Online ISSN

2090-2581

Link

https://scumj.journals.ekb.eg/article_400508.html

Detail API

https://scumj.journals.ekb.eg/service?article_code=400508

Order

2

Type

Original Article

Type Code

938

Publication Type

Journal

Publication Title

Suez Canal University Medical Journal

Publication Link

https://scumj.journals.ekb.eg/

MainTitle

Prevalence of Regular Long-Acting Penicillin Administration as a Prophylaxis against Rheumatic Fever among Ismailia District Students Aged between 5–15 Years

Details

Type

Article

Created At

30 Dec 2024