This review offers a comprehensive examination of the current state of knowledge regarding nanoparticle applications in plant nutrition. By synthesizing existing literature, it aims to analyze significant discoveries, emerging trends, and research gaps. The study focuses on several key topics, including nanotechnology applications, nanotechnology in agriculture, nano-fertilizers, and the superiority of the nanotechnology approach over chelated methods. The review explores the effects of nano-fertilizers on plant growth, yield, and nutrient uptake, emphasizing their potential to address challenges such as low nutrient use efficiency and environmental contamination. Studies demonstrate the effectiveness of nano-fertilizers in enhancing plant growth and productivity, particularly under stress conditions, with significant improvements observed in various crop parameters. Furthermore, the review highlights the advantages of nanotechnology over traditional methods, showcasing its potential to revolutionize agricultural practices. Nano-fertilizers exhibit superior performance compared to conventional fertilizers, offering precise and controlled nutrient delivery, leading to enhanced plant growth and environmental sustainability. Generally, nanotechnology holds immense promise for sustainable agriculture, offering innovative solutions to improve crop productivity, environmental sustainability, and food security. Harnessing the potential of nano-fertilizers could lead to significant advancements in agricultural practices, benefiting both farmers and the environment. However, further research is needed to fully understand the long-term effects and implications of nano-fertilizers on crop production and ecosystem health.