This investigation was carried out at the farm of Sids Agricultural Research Station, ARC, in Beni Suef Governorate in two successive seasons study the effect of different levels of organic manure and NPK application on quality, quantity and storability of onion (Allium cipa L) as well as some physio-chemical soil properties at harvest stage. A split plot design was used in the experiment, where the main plots were located with organic manure (0.0, 24.0 and 48.0 t ha-1) represent without, half and full recommended rates of FYM and the sub plots were represent the NPK fertilizers (0.0, half and full recommended rates). The full recommended NPK rates were 288/75/115 N, P2O5 and K2O kg ha-1 Results show that increasing organic manure levels improved all studied soil properties and fertility after onion harvest, i.e., soil reaction, organic matter, bulk density, soil available N, P and K, except soil salinity which positively responded to FYM application. Also, organic manure application enhanced the onion dry matter, total dissolved solids (TDS), plant height and number of leaves/plant at 90 and 110 days, bulb weight, total yield, culls yield and marketable yield. Increasing NPK levels had positive effect on soil fertility, plant height, number of leaves/plant, bulb weight total yield, culls yield. Whereas dry matter %, T.D.S%, marketable yield and storability responded to NPK levels only at half recommended rate of NPK. Combined high level of organic manure with half recommended rate of NPK gave the best vegetative growth, yield and storability of onion plants.