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389883

Evaluation of Cytotoxicity Effects of the Biocontrol Bacterium Bacillus velezensis BE1

Article

Last updated: 04 Jan 2025

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Abstract

Bacillus velezensis controls plant pathogens and reduces dependence on synthetic pesticides within sustainable agriculture practices. In the current study, the cell suspension of B. velezensis BE1 did not reduce the viability of Vero cells, kidney cells from an African monkey, HFB4 human skin cell line, or WI-38 cells, which are diploid human fibroblasts generated from the lung cell of a female fetus, at concentrations ranging from 19 × 1011 to 0.59 × 1011. Additionally, the study indicated that cell suspensions of B. velezensis BE1 exhibited no cytotoxicity at any concentration tested on the three cell lines. Cytotoxicity levels ranged between 0 and 1.45 % for Vero cells, 0 and 0.91 % for WI-38 cells, and 0.40 to 6.27 % for HFB4 cells. These findings confirm the biosafety of the endophytic bacterium B. velezensis BE1 and could be used for the control of plant pathogens in both pre- and postharvest diseases.

DOI

10.21608/jppp.2024.330398.1274

Keywords

cytotoxic effects, Endophytic bacteria, biological control, biosafety

Authors

First Name

Esraa

Last Name

Aboelez

MiddleName

M.

Affiliation

Plant Pathology Department, Faculty of Agriculture, Mansoura University, Mansoura 35516, Egypt

Email

-

City

-

Orcid

-

First Name

M.

Last Name

Selim

MiddleName

A. E.

Affiliation

Agricultural Microbiology Department, Faculty of Agriculture, Mansoura University, Mansoura 35516, Egypt

Email

m.selimrrtc@gmail.com

City

-

Orcid

-

First Name

Safaa

Last Name

Yousef

MiddleName

A.

Affiliation

Mycology Research and Plant Disease Survey Department, Plant Pathology Research Institute, Agricultural Research Center, Giza 12619, Egypt

Email

safaaphd3@yahoo.com

City

-

Orcid

-

First Name

Safaa

Last Name

Hamza

MiddleName

-

Affiliation

Plant Pathology Department, Faculty of Agriculture, Mansoura University, Mansoura 35516, Egypt

Email

gentleplant4@yahoo.com

City

-

Orcid

-

First Name

Y.

Last Name

Shabana

MiddleName

M.

Affiliation

-Plant Pathology Department, Faculty of Agriculture, Mansoura University, Mansoura 35516, Egypt -National Agricultural and Food Research Council, Academy of Scientific Research and Technology, Cairo, Egypt

Email

yassershabana2@yahoo.com

City

-

Orcid

-

First Name

E.

Last Name

Elsherbiny

MiddleName

A.

Affiliation

Plant Pathology Department, Faculty of Agriculture, Mansoura University, Mansoura 35516, Egypt

Email

sherbiny@mans.edu.eg

City

Mansoura

Orcid

0000-0003-1778-2048

Volume

15

Article Issue

10

Related Issue

50797

Issue Date

2024-10-01

Receive Date

2024-10-31

Publish Date

2024-10-01

Page Start

359

Page End

362

Print ISSN

2090-3677

Online ISSN

2090-3758

Article File

JPPP_Volume 15_Issue 10_Pages 359-362.pdf

PDF . 473.4kB

Link

https://jppp.journals.ekb.eg/article_389883.html

Detail API

https://jppp.journals.ekb.eg/service?article_code=389883

Order

8

Type

Original Article

Type Code

888

Publication Type

Journal

Publication Title

Journal of Plant Protection and Pathology

Publication Link

https://jppp.journals.ekb.eg/

MainTitle

Evaluation of Cytotoxicity Effects of the Biocontrol Bacterium Bacillus velezensis BE1

Details

Type

Article

Created At

30 Dec 2024