The toxic influence of boric, salicylic and sulfonic organic acids and the ammonium hydroxide, copper sulfate, and urea as fertilizers were evaluated against the adult snails of Eobania vermiculata for 21 days by spraying technique under the laboratory conditions. Organic acids and fertilizers were decomposing in the soil accelerated than pesticides; four recommended concentrations (0.5, 1, 1.5 and 2%) were opted for each acid and fertilizer and selected as low concentrations to avoid any noxious impact against plants. Moreover, efficacy of the binary mixing of organic acids with fertilizers at LC25 against the adult snail individuals was also investigated. The utmost mean mortality of snails was remarked at the concentration of 2% of all tested compounds, which attained 52.00, 82.66 and 83.33% for boric, salicylic and sulfonic acids while it was 95.33, 94.00, and 50.00 for ammonium hydroxide, copper sulfate, and urea, consecutively. Based on LC50, the efficiency of tested compounds could be arranged in descending order sequentially to ammonium hydroxide, copper sulfate, sulfonic acid, salicylic acid, boric acid and urea. The binary mixture of sulfonic acid with urea and salicylic acid with ammonium hydroxide achieved the highest molluscicidal effect against snails in comparison with the other tested mixtures, accomplished 100% mortality of snails. On the contrary, the binary mixing of salicylic acid with copper sulfate achieved the lowest mean mortality which it was only 12.66%.