One abiotic environmental stressor that decrease wheat yield globally is drought. In the current study, 9x9 diallel schema excluding reciprocals were formed in 2021/2022 growing season. In 2022/2023 season, Parents and 36 crosses assessed (organized in RCBD design) under two main water regimes: well-watered (five irrigations) and water-deficient (one surface irrigations). The findings showed that, for all traits under study, there were significant (p ≤ 0.01) variations in genotypes and their partitioning under regular irrigation treatment and drought. For every trait under study in both environments, the mean squares (MS) of both types of combining ability (GCA and SCA) were significant. The magnitudes of the GCA/SCA ratios showed that additive and additive by additive gene action types might account for the majority of the total genetic variability linked to these characters. The parental.3 was a good general combiner for number of spikes plant-1 and grain yield plant-1, while, parental variety P7 was the best general combiner for plant height, number of kernels spike-1 and 1000 kernel weight. The highest desirable SCA effects were obtained with P1×P7 for plant height, P1×P5 for number of spike plant-1, P3×P8 for number of kernels spike-1, P6×P7 for 1000- kernel weight, P6×P9 for grain yield under drought stress.  The cross P2 x P4 showed the greatest significant and positive heterosis, reached 48.97**,84.25** and 68.63**,33.83 for mid-parent and better-parent in each of drought and normal environment, respectively. The mean squares due to genotypes of (SI) were highly significant SI for most studied traits except spike length.