The study was carried out at El-Gemmeiza Agricultural Research Station (ARC), El- Gharbia Governorate, Egypt, during 2019/2020 and 2020/2021 growing seasons to study the effect of three irrigation intervals on morphological and physiological characters of ten bread wheat cultivars. A split - plot design with four replications was performed, the main plots included the three irrigation intervals i.e., irrigation every 20, 30 and 40 days and the ten bread wheat cultivars (Giza171, Sakha 95, Giza 168, Sids14, Misr 3, Misr 2, Sakha 94, Gemmeiza 11, Shandweel 1 and Gemmeiza 12) were placed in sub-plots. Irrigation intervals every 40 days caused a decrease in all of the studied characters (days to maturity, days to heading, grain filling rate, grain filling period, leaf area index, plant height, crop growth rate, relative growth rate, transpiration rate and relative water content) except for total chlorophyll content, stomatal resistance, leaf temperature and proline content in both seasons. The highest value of stomatal resistance was detected in Sakha 95 and that of total chlorophyll content and proline content were found in Misr 3 at irrigation intervals every 40. Thus, Misr 3 and Sakha 95 are suitable cultivars for conditions of water stress.