The research was carried out in the practical domain of Aromatic and Medicinal Plants, Faculty of Agriculture, Mansoura University, during 2021–2022 and 2022–2023 seasons. The present study aimed to investigate the effect of foliar application of some stimulants (Chitosan, Glycine betaine, and potassium silicate) on some vegetative growth (plant height and leaves dry weight), essential oil percentage, essential oil content, and its constituents of sage plants under different irrigation interval conditions (plants irrigated every 3, 6, and 9 days). The results showed that irrigation of plants every 3 and 6 days was effective in increasing the productivity of plant height and leaf dry weight; however, essential oil percentage, essential oil content, and essential oil constituents of sage were highest during the 9-day irrigation interval. On the other hand, foliar application with potassium silicate was more effective than chitosan, and glycine betaine improved the productivity of vegetative growth, essential oil percentage, essential oil content, and its components of sage plant